2026년
한국질량분석학회 여름학술대회 및 총회
2026. 08.19 (수) ~ 2026. 08.21 (금)
창원컨벤션센터(CECO)
초록검색
| 제목 | Untargeted Metabolomic Characterization and Anti-Inflammatory Effects of Aralia elata Young Leaves and Twigs |
|---|---|
| 작성자 | 장서영 (순천대학교) |
| 발표구분 | 포스터발표 |
| 발표분야 | 4. Medical / Pharmaceutical Science |
| 발표자 |
Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) Eunyeong Jeong (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea , AI Bio Autonomous Research, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea) |
| 주저자 | Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) |
| 교신저자 |
Mina Lee (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea , College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, 255 Jungangno, Suncheon, Jeonna) |
| 저자 |
Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) Eunyeong Jeong (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea , AI Bio Autonomous Research, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea) Duc Dat Le (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea , College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, 255 Jungangno, Suncheon, Jeonna) Thinhulinh Dang (College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, 255 Jungangno, Suncheon, Jeonnam 57922, Republic of Korea, Honam Regional Future Drug Development Convergence Education & Research Division (BK21 ) Thientam Dinh (College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, 255 Jungangno, Suncheon, Jeonnam 57922, Republic of Korea, Honam Regional Future Drug Development Convergence Education & Research Division (BK21) Soojung Yu (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea ) Mina Lee (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam 57922, Republic of Korea , College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, 255 Jungangno, Suncheon, Jeonna) |
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Aralia elata (Miq.) Seem. is a deciduous shrub native to East Asia that has been used in traditional medicine, utilizing its bark and roots, preparing decoctions or poultices to address a range of inflammatory conditions such as rheumatism, joint pain, bruises, swellings, and various skin inflammations. However, there is limited research on anti-inflammatory effects of the young twigs and leaves of A. elata. This study revealed the anti-inflammatory effect of extracts of A. elata in suppressing NO production induced by LPS-activated RAW264.7 cells. Additionally, LC-MS/MS coupled with a molecular network was employed to identify the chemical constituents from A. elata. As a result, 39 putative compounds were annotated from A. elata extracts, including fatty acids, phenolics, terpenoids, flavonoids, alkaloids, organic acids, and others, by analyzing the mass precursor ions and fragmentation pathways of peaks detected in the chromatograms and comparing them to those of standards or those of reference mass spectra obtained from the public mass databases. Our findings highlight the anti-inflammatory potential of A. elata in traditional medicine and propose the active compounds responsible for its anti-inflammatory effects, which need to be confirmed in further studies. |
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