박세민 (경상국립대학교 첨단소재분석지원센터)

고필옥 (경상국립대학교 수의과대학 수의조직학연구실)

박세민 (경상국립대학교 첨단소재분석지원센터)

배동원 (경상국립대학교 첨단소재분석지원센터)

이경희 (경상국립대학교 첨단소재분석지원센터)

최성길 (경상국립대학교 식품공학부 식품공정공학연구실)

고필옥 (경상국립대학교 수의과대학 수의조직학연구실)

Drying methods can significantly influence the chemical composition and functional quality of plant-derived materials. This study aimed to compare the profiles of major secondary metabolites in persimmon (Diospyros kaki) peel subjected to different drying techniques— vacuum drying, freeze drying, and vacuum hot air drying—using ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS). Targeted secondary metabolomic profiling identified marked differences in polyphenols, amino acid metabolites, fatty acid amides and lysophosphatidylcholines depending on the drying method. Multivariate statistical analyses, including principal component analysis (PCA) and heat map, effectively distinguished between the drying treatments based on their metabolite compositions. Notably, freeze drying was shown to maintain higher levels of heat-sensitive phenolic compounds, while hot air drying and vacuum drying resulted in the formation of distinct degradation or transformation products. These findings deliver critical insights into the effects of various drying strategies on the bioactive compound content in persimmon peel, supporting informed decision-making in the processing of functional food and nutraceutical applications.

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