2025년
한국질량분석학회 여름학술대회 및 총회
2025. 08.27 (수) ~ 2025. 08.29 (금)
부산항국제전시컨벤션센터(BPEX)
초록검색
| 제목 | Improving Compound Identification and Quantitation using ZT Scan DIA on a Novel QTOF Instrument |
|---|---|
| 작성자 | 최도영 (SCIEX) |
| 발표구분 | 포스터발표 |
| 발표분야 | 1. Fundamental & Instrumentation |
| 발표자 |
Doyoung Choi (SCIEX KOREA) |
| 주저자 | Doyoung Choi (SCIEX KOREA) |
| 교신저자 | |
| 저자 |
Doyoung Choi (SCIEX KOREA) |
|
Data-independent acquisition (DIA) using ZT Scan DIA allows correlation of fragment ions with associated precursor ions in addition to the benefits of SWATH DIA. SWATH DIA uses precursor isolation windows that are typically 5–50 Da. When two or more compounds fall in the same SWATH DIA precursor isolation window, deconvolution of the MS/MS is usually only possible using techniques based on LC profile correlation. Compared to SWATH DIA, ZT Scan DIA provides additional selectivity in the quadrupole dimension that is complementary to retention time and fragment ion m/z for more reliable compound identification. Here, we demonstrate that ZT Scan DIA combined with high-flow chromatography results in fast, sensitive and quantitatively precise compounds identification and quantitation from NIST 1950 plasma. |
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